Publications

Here, the full list of UMR-5234 publications.


2024

Batisse C, Lapaillerie D, Humbert N, Real E, Zhu R, Mély Y, Parissi V, Ruff M, Batisse J. Integrase-LEDGF/p75 complex triggers the formation of biomolecular condensates that modulate HIV-1 integration efficiency in vitro. J Biol Chem. 2024 300, 107374. PubMed PMID:38762180

Asencio C, Hervé P, Morand P, Oliveres Q, Morel CA, Prouzet-Mauleon V, Biran M, Monic S, Bonhivers M, Robinson DR, Ouellette M, Rivière L, Bringaud F, Tetaud E. Streptococcus pyogenes Cas9 ribonucleoprotein delivery for efficient, rapid and marker-free gene editing in Trypanosoma and Leishmania. Mol Microbiol. 2024 121, 1079-1094. PubMed PMID:38558208

Kagambèga AB, Dembélé R, Traoré O, Wane AA, Mohamed AH, Coulibaly H, Fall C, Bientz L, M'Zali F, Mayonnove L, Barro N, Dubois V, Dieye Y. Isolation and Characterization of Environmental Extended Spectrum β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae from Ouagadougou, Burkina Faso. Pharmaceuticals (Basel). 2024 17, . PubMed PMID:38543091

Santerre Henriksen A, Jeannot K, Oliver A, Perry JD, Pletz MW, Stefani S, Morrissey I, Longshaw C, ARTEMIS Study Investigators. In vitro activity of cefiderocol against European Pseudomonas aeruginosa and Acinetobacter spp., including isolates resistant to meropenem and recent β-lactam/β-lactamase inhibitor combinations. Microbiol Spectr. 2024 12, e0383623. PubMed PMID:38483164

Meyer Sauteur PM, Beeton ML, European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Mycoplasma and Chlamydia Infections (ESGMAC), and the ESGMAC Mycoplasma pneumoniae Surveillance (MAPS) study group. Pneumonia outbreaks due to re-emergence of Mycoplasma pneumoniae. Lancet Microbe. 2024 5, e514. PubMed PMID:38342111

Murigneux E, Softic L, Aubé C, Grandi C, Judith D, Bruce J, Le Gall M, Guillonneau F, Schmitt A, Parissi V, Berlioz-Torrent C, Meertens L, Hansen MMK, Gallois-Montbrun S. Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly. Nat Commun. 2024 15, 640. PubMed PMID:38245532

Richard E, Darracq B, Littner E, Vit C, Whiteway C, Bos J, Fournes F, Garriss G, Conte V, Lapaillerie D, Parissi V, Rousset F, Skovgaard O, Bikard D, Rocha EPC, Mazel D, Loot C. Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems. Sci Adv. 2024 10, eadj3498. PubMed PMID:38215203

Loot C, Millot GA, Richard E, Littner E, Vit C, Lemoine F, Néron B, Cury J, Darracq B, Niault T, Lapaillerie D, Parissi V, Rocha EPC, Mazel D. Integron cassettes integrate into bacterial genomes via widespread non-classical attG sites. Nat Microbiol. 2024 9, 228-240. PubMed PMID:38172619

De Rache A, Marquevielle J, Bouaziz S, Vialet B, Andreola ML, Mergny JL, Amrane S. Structure of a DNA G-quadruplex that Modulates SP1 Binding Sites Architecture in HIV-1 Promoter. J Mol Biol. 2024 436, 168359. PubMed PMID:37952768

Dacheux D, Martinez G, Broster Reix CE, Beurois J, Lores P, Tounkara M, Dupuy JW, Robinson DR, Loeuillet C, Lambert E, Wehbe Z, Escoffier J, Amiri-Yekta A, Daneshipour A, Hosseini SH, Zouari R, Mustapha SFB, Halouani L, Jiang X, Shen Y, Liu C, Thierry-Mieg N, Septier A, Bidart M, Satre V, Cazin C, Kherraf ZE, Arnoult C, Ray PF, Toure A, Bonhivers M, Coutton C. Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function. Elife. 2023 12, . PubMed PMID:37934199

Puges M, Carrer M, Caradu C, Bérard X, Cazanave C, VIP study group. Sonicate Fluid Inoculation Into Blood Culture Bottles for Vascular Graft and Endograft Infection Microbiological Diagnosis. Eur J Vasc Endovasc Surg. 2024 67, 518-519. PubMed PMID:37923190

2023

Bébéar C, Pereyre S, Berçot B, Cazanave C. Managing bacterial sexually transmitted infections (STIs) and preventing HIV/STIs in Europe. Lancet Reg Health Eur. 2023 34, 100760. PubMed PMID:37927429

Kagambèga AB, Dembélé R, Bientz L, M'Zali F, Mayonnove L, Mohamed AH, Coulibaly H, Barro N, Dubois V. Detection and Characterization of Carbapenemase-Producing Escherichia coli and Klebsiella pneumoniae from Hospital Effluents of Ouagadougou, Burkina Faso. Antibiotics (Basel). 2023 12, . PubMed PMID:37887195

Taleva G, Husová M, Panicucci B, Hierro-Yap C, Pineda E, Biran M, Moos M, Šimek P, Butter F, Bringaud F, Zíková A. Mitochondrion of the Trypanosoma brucei long slender bloodstream form is capable of ATP production by substrate-level phosphorylation. PLoS Pathog. 2023 19, e1011699. PubMed PMID:37819951

Hervé P, Monic S, Bringaud F, Rivière L. Phospholipases A and Lysophospholipases in protozoan parasites. Microb Cell. 2023 10, 204-216. PubMed PMID:37786811

Guiraud J, Le Roy C, Rideau F, Sirand-Pugnet P, Lartigue C, Bébéar C, Arfi Y, Pereyre S. Improved transformation efficiency in Mycoplasma hominis enables disruption of the MIB-MIP system targeting human immunoglobulins. Microbiol Spectr. 2023 11, e0187323. PubMed PMID:37737635

Pfirmann P, Garrigue I, Chauveau B, Rondeau V, Tumiotto C, Weinmann L, Dubois V, Couzi L, Merville P, Kaminski H, Taton B. Trends in epidemiology and risk factors of opportunistic infections in kidney transplant recipients between 2004 and 2017. Nephrol Dial Transplant. 2024 39, 627-636. PubMed PMID:37667539

Schwartz U, Komatsu T, Huber C, Lagadec F, Baumgartl C, Silberhorn E, Nuetzel M, Rayne F, Basyuk E, Bertrand E, Rehli M, Wodrich H, Laengst G. Changes in adenoviral chromatin organization precede early gene activation upon infection. EMBO J. 2023 42, e114162. PubMed PMID:37641864

Puges M, Bérard X, Vilain S, Pereyre S, Svahn I, Caradu C, Mzali F, Cazanave C. Staphylococcus aureus Adhesion and Biofilm Formation on Vascular Polyester Grafts are Inhibited In Vitro by Triclosan. Eur J Vasc Endovasc Surg. 2023 66, 577-586. PubMed PMID:37482281

Puges M, M'Zali F, Pereyre S, Bébéar C, Cazanave C, Bérard X. A Narrative Review of Experimental Assessment to Study Vascular Biomaterials Infections and Infectability. EJVES Vasc Forum. 2023 59, 49-55. PubMed PMID:37408851

Meyer Sauteur PM, Beeton ML, ESGMAC the ESGMAC MAPS study group. Mycoplasma pneumoniae: gone forever?. Lancet Microbe. 2023 4, e763. PubMed PMID:37393927

Mauro E, Lapaillerie D, Tumiotto C, Charlier C, Martins F, Sousa SF, Métifiot M, Weigel P, Yamatsugu K, Kanai M, Munier-Lehmann H, Richetta C, Maisch M, Dutrieux J, Batisse J, Ruff M, Delelis O, Lesbats P, Parissi V. Modulation of the functional interfaces between retroviral intasomes and the human nucleosome. mBio. 2023 14, e0108323. PubMed PMID:37382440

Puges M, Jauvain M, Vignals C, Dutronc H, Barthod L, Pereyre S, Lehours P, Cazanave C. Pseudomembranous necrotic pharyngotonsillitis: a microbiologic criminal conspiracy. Clin Microbiol Infect. 2023 29, 1289-1290. PubMed PMID:37271193

Tamarelle J, Penaud B, Tyssandier B, Guichoux E, de Barbeyrac B, Peuchant O, Chlazidoxy study group. Effects of azithromycin and doxycycline on the vaginal microbiota of women with urogenital Chlamydia trachomatis infection: a substudy of the Chlazidoxy randomized controlled trial. Clin Microbiol Infect. 2023 29, 1056-1062. PubMed PMID:37100225

Gardette M, Touati A, Laurier-Nadalié C, Bébéar C, Pereyre S. Prevalence of Mycoplasma penetrans in Urogenital Samples From Men Screened for Bacterial Sexually Transmitted Infections. Open Forum Infect Dis. 2023 10, ofad180. PubMed PMID:37082616

Prevel R, Enaud R, Orieux A, Camino A, Sioniac P, M'Zali F, Dubois V, Berger P, Boyer A, Delhaes L, Gruson D. Bridging gut microbiota composition with extended-spectrum beta-lactamase Enterobacteriales faecal carriage in critically ill patients (microbe cohort study). Ann Intensive Care. 2023 13, 25. PubMed PMID:37014580

Sabra A, Biteau N, Dupuy JW, Klopp C, Noël T, Dementhon K. Mediator Subunit Med15 Regulates Cell Morphology and Mating in Candida lusitaniae. J Fungi (Basel). 2023 9, . PubMed PMID:36983501

Guerville F, Vialemaringe M, Cognet C, Duffau P, Lazaro E, Cazanave C, Bonnet F, Leleux O, Rossignol R, Pinson B, Tumiotto C, Gabriel F, Appay V, Déchanet-Merville J, Wittkop L, Faustin B, Pellegrin I, on the behalf of ANRS CO3 Aquitaine / AquiVIH-NA study group. Mechanisms of systemic low-grade inflammation in HIV patients on long-term suppressive antiretroviral therapy: the inflammasome hypothesis. AIDS. 2023 37, 1035-1046. PubMed PMID:36928274

Ingle SM, Miro JM, May MT, Cain LE, Schwimmer C, Zangerle R, Sambatakou H, Cazanave C, Reiss P, Brandes V, Bucher HC, Sabin C, Vidal F, Obel N, Mocroft A, Wittkop L, d'Arminio Monforte A, Torti C, Mussini C, Furrer H, Konopnicki D, Teira R, Saag MS, Crane HM, Moore RD, Jacobson JM, Mathews WC, Geng E, Eron JJ, Althoff KN, Kroch A, Lang R, Gill MJ, Sterne JAC. Early Antiretroviral Therapy Not Associated With Higher Cryptococcal Meningitis Mortality in People With Human Immunodeficiency Virus in High-Income Countries: An International Collaborative Cohort Study. Clin Infect Dis. 2023 77, 64-73. PubMed PMID:36883578

Acquier M, Zabala A, de Précigout V, Delmas Y, Dubois V, de la Faille R, Rubin S, Combe C, M'Zali F, Kaminski H. Performance of real-time PCR in suspected haemodialysis catheter-related bloodstream infection: a proof-of-concept study. Clin Kidney J. 2023 16, 494-500. PubMed PMID:36865002

Abou-Hamdan M, Saleh R, Mani S, Dournaud P, Metifiot M, Blondot ML, Andreola ML, Abdel-Sater F, De Reggi M, Gressens P, Laforge M. Potential antiviral effects of pantethine against SARS-CoV-2. Sci Rep. 2023 13, 2237. PubMed PMID:36754974

2022

Berçot B, Caméléna F, Mérimèche M, Jacobsson S, Sbaa G, Mainardis M, Valin C, Molina JM, Bébéar C, Chazelle E, Lot F, Golparian D, Unemo M. Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022. Euro Surveill. 2022 27, . PubMed PMID:36695466

Touati A, Bébéar C, Peuchant O. Update on the availability of commercialized real-time PCR assays for the diagnosis of Lymphogranuloma venereum. Clin Microbiol Infect. 2023 29, 548-549. PubMed PMID:36572103

Lorenzen E, Contreras V, Olsen AW, Andersen P, Desjardins D, Rosenkrands I, Juel HB, Delache B, Langlois S, Delaugerre C, Joubert C, Dereuddre-Bosquet N, Bébéar C, De Barbeyrac B, Touati A, McKay PF, Shattock RJ, Le Grand R, Follmann F, Dietrich J. Multi-component prime-boost Chlamydia trachomatis vaccination regimes induce antibody and T cell responses and accelerate clearance of infection in a non-human primate model. Front Immunol. 2022 13, 1057375. PubMed PMID:36505459

Trindade S, De Niz M, Costa-Sequeira M, Bizarra-Rebelo T, Bento F, Dejung M, Narciso MV, López-Escobar L, Ferreira J, Butter F, Bringaud F, Gjini E, Figueiredo LM. Slow growing behavior in African trypanosomes during adipose tissue colonization. Nat Commun. 2022 13, 7548. PubMed PMID:36481558

Amrane S, Jaubert C, Bedrat A, Rundstadler T, Recordon-Pinson P, Aknin C, Guédin A, De Rache A, Bartolucci L, Diene I, Lemoine F, Gascuel O, Pratviel G, Mergny JL, Andreola ML. Deciphering RNA G-quadruplex function during the early steps of HIV-1 infection. Nucleic Acids Res. 2022 50, 12328-12343. PubMed PMID:36453997

Pereyre S, Laurier-Nadalié C, Le Roy C, Guiraud J, Dolzy A, Hénin N, Gardette M, Bébéar C, investigator group. Prevalence of macrolide and fluoroquinolone resistance-associated mutations in Mycoplasma genitalium in metropolitan and overseas France. Sex Transm Infect. 2023 99, 254-260. PubMed PMID:36413349

Gardette M, Hénin N, Le Roy C, Guiraud J, Touati A, Bébéar C, Pereyre S. Clinical Performance of Three Commercial Molecular Diagnostic Assays for the Detection of Fluoroquinolone Resistance-Associated Mutations in Mycoplasma genitalium. J Clin Microbiol. 2022 60, e0113522. PubMed PMID:36321820

Roumégous C, Abou Hammoud A, Fuster D, Dupuy JW, Blancard C, Salin B, Robinson DR, Renesto P, Tardieux I, Frénal K. Identification of new components of the basal pole of Toxoplasma gondii provides novel insights into its molecular organization and functions. Front Cell Infect Microbiol. 2022 12, 1010038. PubMed PMID:36310866

Mhaya A, Trabelsi R, Aillerie S, M'Zali F, Bégu D, Tounsi S, Gdoura R, Arpin C. Detection of Clones B2-ST131-C2 and A-ST617 in Escherichia coli Producing Both CTX-M-15 and CTX-M-27 from Tunisian Community Patients. Antibiotics (Basel). 2022 11, . PubMed PMID:36289987

Viriot D, Lucas E, de Barbeyrac B, Bébéar C, Fouéré S, Dupin N, Bertolotti A, Berçot B, Cazanave C, Delmas G, Pillonel J, Lot F, Ngangro NN. Use of healthcare reimbursement data to monitor bacterial sexually transmitted infection testing in France, 2006 to 2020. Euro Surveill. 2022 27, . PubMed PMID:36177869

Guiraud J, Helary M, Le Roy C, Elguero E, Pereyre S, Bébéar C. Molecular Typing Reveals Distinct Mycoplasma genitalium Transmission Networks among a Cohort of Men Who Have Sex with Men and a Cohort of Women in France. Microorganisms. 2022 10, . PubMed PMID:36014005

Garzaro M, Zhao LP, De Castro N, Mercier-Delarue S, Camelena F, Pereyre S, Gardette M, Berçot B, Malphettes M, Bébéar C, Bouaziz JD, Le Goff J, Galicier L, Salmona M. Metagenomic next-generation sequencing restores the diagnosis of a rare infectious complication of B cell depletion. Eur J Clin Microbiol Infect Dis. 2022 41, 1269-1273. PubMed PMID:36001207

Meyer Sauteur PM, Chalker VJ, Berger C, Nir-Paz R, Beeton ML, ESGMAC and the ESGMAC–MyCOVID study group. Mycoplasma pneumoniae beyond the COVID-19 pandemic: where is it?. Lancet Microbe. 2022 3, e897. PubMed PMID:35964636

Li H, Ernst C, Kolonko-Adamska M, Greb-Markiewicz B, Man J, Parissi V, Ng BW. Phase separation in viral infections. Trends Microbiol. 2022 30, 1217-1231. PubMed PMID:35902318

Rocchi C, Gouet P, Parissi V, Fiorini F. The C-Terminal Domain of HIV-1 Integrase: A Swiss Army Knife for the Virus?. Viruses. 2022 14, . PubMed PMID:35891378

Delafoy M, Goutines J, Fourmont AM, Birgy A, Chomton M, Levy M, Naudin J, Zafrani L, Le Mouel L, Yakouben K, Cointe A, Caseris M, Lafaurie M, Bonacorsi S, Mechinaud F, Pereyre S, Boissel N, Baruchel A. Case Report: Hyperammonemic Encephalopathy Linked to Ureaplasma spp. and/or Mycoplasma hominis Systemic Infection in Patients Treated for Leukemia, an Emergency Not to Be Missed. Front Oncol. 2022 12, 912695. PubMed PMID:35875088

Lapaillerie D, Charlier C, Guyonnet-Dupérat V, Murigneux E, Fernandes HS, Martins FG, Magalhães RP, Vieira TF, Richetta C, Subra F, Lebourgeois S, Charpentier C, Descamps D, Visseaux B, Weigel P, Favereaux A, Beauvineau C, Buron F, Teulade-Fichou MP, Routier S, Gallois-Montbrun S, Meertens L, Delelis O, Sousa SF, Parissi V. Selection of Bis-Indolyl Pyridines and Triphenylamines as New Inhibitors of SARS-CoV-2 Cellular Entry by Modulating the Spike Protein/ACE2 Interfaces. Antimicrob Agents Chemother. 2022 66, e0008322. PubMed PMID:35861550

Pied N, Daussy CF, Denis Z, Ragues J, Faure M, Iggo R, Tschan MP, Roger B, Rayne F, Wodrich H. TBK1 is part of a galectin 8 dependent membrane damage recognition complex and drives autophagy upon Adenovirus endosomal escape. PLoS Pathog. 2022 18, e1010736. PubMed PMID:35857795

Richetta C, Subra F, Malet I, Leh H, Charpentier C, Corona A, Collin G, Descamps D, Deprez E, Parissi V, Calvez V, Tramontano E, Marcelin AG, Delelis O. Mutations in the 3'-PPT Lead to HIV-1 Replication without Integration. J Virol. 2022 96, e0067622. PubMed PMID:35758669

Beucher G, Blondot ML, Celle A, Pied N, Recordon-Pinson P, Esteves P, Faure M, Métifiot M, Lacomme S, Dacheux D, Robinson DR, Längst G, Beaufils F, Lafon ME, Berger P, Landry M, Malvy D, Trian T, Andreola ML, Wodrich H. Bronchial epithelia from adults and children: SARS-CoV-2 spread via syncytia formation and type III interferon infectivity restriction. Proc Natl Acad Sci U S A. 2022 119, e2202370119. PubMed PMID:35749382

2021

Tounkara M, Boulangé A, Thonnus M, Bringaud F, Bélem AMG, Bengaly Z, Thévenon S, Berthier D, Rivière L. Novel protein candidates for serodiagnosis of African animal trypanosomosis: Evaluation of the diagnostic potential of lysophospholipase and glycerol kinase from Trypanosoma brucei. PLoS Negl Trop Dis. 2021 15, e0009985. PubMed PMID:34919562

Bringaud F, Plazolles N, Pineda E, Asencio C, Villafraz O, Millerioux Y, Rivière L, Tetaud E. Glycerol, a possible new player in the biology of trypanosomes. PLoS Pathog. 2021 17, e1010035. PubMed PMID:34855923

Got FEB, Recordon-Pinson P, Loubano-Voumbi G, Ebourombi D, Blondot ML, Metifiot M, Ondzotto G, Andreola ML. Absence of Resistance Mutations in the Integrase Coding Region among ART-Experienced Patients in the Republic of the Congo. Microorganisms. 2021 9, . PubMed PMID:34835480

Broster Reix CE, Florimond C, Cayrel A, Mailhé A, Agnero-Rigot C, Landrein N, Dacheux D, Havlicek K, Bonhivers M, Morriswood B, Robinson DR. Bhalin, an Essential Cytoskeleton-Associated Protein of Trypanosoma brucei Linking TbBILBO1 of the Flagellar Pocket Collar with the Hook Complex. Microorganisms. 2021 9, . PubMed PMID:34835460

Lagadec F, Carlon-Andres I, Ragues J, Port S, Wodrich H, Kehlenbach RH. CRM1 Promotes Capsid Disassembly and Nuclear Envelope Translocation of Adenovirus Independently of Its Export Function. J Virol. 2022 96, e0127321. PubMed PMID:34757845

Broster Reix CE, Ramanantsalama MR, Di Primo C, Minder L, Bonhivers M, Dacheux D, Robinson DR. Intrabody-Induced Cell Death by Targeting the T. brucei Cytoskeletal Protein TbBILBO1. Microbiol Spectr. 2021 9, e0091521. PubMed PMID:34704826

Lapaillerie D, Lelandais B, Mauro E, Lagadec F, Tumiotto C, Miskey C, Ferran G, Kuschner N, Calmels C, Métifiot M, Rooryck C, Ivics Z, Ruff M, Zimmer C, Lesbats P, Toutain J, Parissi V. Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75. Nucleic Acids Res. 2021 49, 11241-11256. PubMed PMID:34634812

Oldenburg SH, Buisson L, Beneyton T, Pekin D, Thonnus M, Bringaud F, Rivière L, Baret JC. Confining Trypanosoma brucei in emulsion droplets reveals population variabilities in division rates and improves in vitro cultivation. Sci Rep. 2021 11, 18192. PubMed PMID:34521865

Torres C, Garling A, Taouji S, Calmels C, Andreola ML, Métifiot M. Targeting the Integrated Stress Response Kinase GCN2 to Modulate Retroviral Integration. Molecules. 2021 26, . PubMed PMID:34500856

Andreola ML, Becquart F, Jomaa W, Verhoeven PO, Baldacchino G, Hemour S, D-Mask consortium. The properties of hot household hygroscopic materials and their potential use for non-medical facemask decontamination. PLoS One. 2021 16, e0255148. PubMed PMID:34492026

Allmann S, Wargnies M, Plazolles N, Cahoreau E, Biran M, Morand P, Pineda E, Kulyk H, Asencio C, Villafraz O, Rivière L, Tetaud E, Rotureau B, Mourier A, Portais JC, Bringaud F. Glycerol suppresses glucose consumption in trypanosomes through metabolic contest. PLoS Biol. 2021 19, e3001359. PubMed PMID:34388147

Isch C, Majneri P, Landrein N, Pivovarova Y, Lesigang J, Lauruol F, Robinson DR, Dong G, Bonhivers M. Structural and functional studies of the first tripartite protein complex at the Trypanosoma brucei flagellar pocket collar. PLoS Pathog. 2021 17, e1009329. PubMed PMID:34339455

Tantale K, Garcia-Oliver E, Robert MC, L'Hostis A, Yang Y, Tsanov N, Topno R, Gostan T, Kozulic-Pirher A, Basu-Shrivastava M, Mukherjee K, Slaninova V, Andrau JC, Mueller F, Basyuk E, Radulescu O, Bertrand E. Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting. Nat Commun. 2021 12, 4503. PubMed PMID:34301927

Daussy CF, Pied N, Wodrich H. Understanding Post Entry Sorting of Adenovirus Capsids; A Chance to Change Vaccine Vector Properties. Viruses. 2021 13, . PubMed PMID:34202573

Corrales RM, Vaselek S, Neish R, Berry L, Brunet CD, Crobu L, Kuk N, Mateos-Langerak J, Robinson DR, Volf P, Mottram JC, Sterkers Y, Bastien P. The kinesin of the flagellum attachment zone in Leishmania is required for cell morphogenesis, cell division and virulence in the mammalian host. PLoS Pathog. 2021 17, e1009666. PubMed PMID:34143858

Ferté T, Ramel V, Cazanave C, Lafon ME, Bébéar C, Malvy D, Georges-Walryck A, Dehail P. Accuracy of COVID-19 rapid antigenic tests compared to RT-PCR in a student population: The StudyCov study. J Clin Virol. 2021 141, 104878. PubMed PMID:34134035

Walrad PB, Field MC, Navarro M, Robinson DR. Kinetoplastid cell biology and genetics, from the 2020 British Society for Parasitology Trypanosomiasis and Leishmaniasis symposium, Granada, Spain. Parasitology. 2021 148, 1119-1124. PubMed PMID:34120664

Messore A, Corona A, Madia VN, Saccoliti F, Tudino V, De Leo A, Ialongo D, Scipione L, De Vita D, Amendola G, Novellino E, Cosconati S, Métifiot M, Andreola ML, Esposito F, Grandi N, Tramontano E, Costi R, Di Santo R. Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase. J Med Chem. 2021 64, 8579-8598. PubMed PMID:34106711

Vit C, Richard E, Fournes F, Whiteway C, Eyer X, Lapaillerie D, Parissi V, Mazel D, Loot C. Cassette recruitment in the chromosomal Integron of Vibrio cholerae. Nucleic Acids Res. 2021 49, 5654-5670. PubMed PMID:34048565

Villafraz O, Baudouin H, Mazet M, Kulyk H, Dupuy JW, Pineda E, Botté C, Inaoka DK, Portais JC, Bringaud F. The Trypanosome UDP-Glucose Pyrophosphorylase Is Imported by Piggybacking into Glycosomes, Where Unconventional Sugar Nucleotide Synthesis Takes Place. mBio. 2021 12, e0037521. PubMed PMID:34044588

2020

Fleury H, Caldato S, Recordon-Pinson P, Thebault P, Guidicelli GL, Hessamfar M, Morlat P, Bonnet F, Visentin J. ART-Treated Patients Exhibit an Adaptive Immune Response against the HFVAC Peptides, a Potential HIV-1 Therapeutic Vaccine (Provir/Latitude45 Study). Viruses. 2020 12, . PubMed PMID:33167335

Daussy CF, Wodrich H. "Repair Me if You Can": Membrane Damage, Response, and Control from the Viral Perspective. Cells. 2020 9, . PubMed PMID:32906744

Zhang W, Mese K, Schellhorn S, Bahlmann N, Mach N, Bunz O, Dhingra A, Hage E, Lafon ME, Wodrich H, Heim A, Ehrhardt A. High-Throughput Cloning and Characterization of Emerging Adenovirus Types 70, 73, 74, and 75. Int J Mol Sci. 2020 21, . PubMed PMID:32887347

Kumar A, Planchais C, Fronzes R, Mouquet H, Reyes N. Binding mechanisms of therapeutic antibodies to human CD20. Science. 2020 369, 793-799. PubMed PMID:32792392

Mochizuki K, Inaoka DK, Mazet M, Shiba T, Fukuda K, Kurasawa H, Millerioux Y, Boshart M, Balogun EO, Harada S, Hirayama K, Bringaud F, Kita K. The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei. Biochim Biophys Acta Bioenerg. 2020 1861, 148283. PubMed PMID:32763239

Frénal K, Krishnan A, Soldati-Favre D. The Actomyosin Systems in Apicomplexa. Adv Exp Med Biol. 2020 1239, 331-354. PubMed PMID:32451865

Messore A, Corona A, Madia VN, Saccoliti F, Tudino V, De Leo A, Scipione L, De Vita D, Amendola G, Di Maro S, Novellino E, Cosconati S, Métifiot M, Andreola ML, Valenti P, Esposito F, Grandi N, Tramontano E, Costi R, Di Santo R. Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase. ACS Med Chem Lett. 2020 11, 798-805. PubMed PMID:32435387

Dogga SK, Frénal K. Two palmitoyl acyltransferases involved sequentially in the biogenesis of the inner membrane complex of Toxoplasma gondii. Cell Microbiol. 2020 22, e13212. PubMed PMID:32329212

Carlon-Andres I, Lagadec F, Pied N, Rayne F, Lafon ME, Kehlenbach RH, Wodrich H. Nup358 and Transportin 1 Cooperate in Adenoviral Genome Import. J Virol. 2020 94, . PubMed PMID:32161167

Laurian R, Jacot-des-Combes C, Bastian F, Dementhon K, Cotton P. Carbon metabolism snapshot by ddPCR during the early step of Candida albicans phagocytosis by macrophages. Pathog Dis. 2020 78, . PubMed PMID:32129841

Vidilaseris K, Landrein N, Pivovarova Y, Lesigang J, Aeksiri N, Robinson DR, Bonhivers M, Dong G. Crystal structure of the N-terminal domain of the trypanosome flagellar protein BILBO1 reveals a ubiquitin fold with a long structured loop for protein binding. J Biol Chem. 2020 295, 1489-1499. PubMed PMID:31882537

Genoveso MJ, Hisaoka M, Komatsu T, Wodrich H, Nagata K, Okuwaki M. Formation of adenovirus DNA replication compartments and viral DNA accumulation sites by host chromatin regulatory proteins including NPM1. FEBS J. 2020 287, 205-217. PubMed PMID:31365788

2019

Pied N, Wodrich H. Imaging the adenovirus infection cycle. FEBS Lett. 2019 593, 3419-3448. PubMed PMID:31758703

Lorès P, Dacheux D, Kherraf ZE, Nsota Mbango JF, Coutton C, Stouvenel L, Ialy-Radio C, Amiri-Yekta A, Whitfield M, Schmitt A, Cazin C, Givelet M, Ferreux L, Fourati Ben Mustapha S, Halouani L, Marrakchi O, Daneshipour A, El Khouri E, Do Cruzeiro M, Favier M, Guillonneau F, Chaudhry M, Sakheli Z, Wolf JP, Patrat C, Gacon G, Savinov SN, Hosseini SH, Robinson DR, Zouari R, Ziyyat A, Arnoult C, Dulioust E, Bonhivers M, Ray PF, Touré A. Mutations in TTC29, Encoding an Evolutionarily Conserved Axonemal Protein, Result in Asthenozoospermia and Male Infertility. Am J Hum Genet. 2019 105, 1148-1167. PubMed PMID:31735292

Aknin C, Smith EA, Marchand C, Andreola ML, Pommier Y, Metifiot M. Discovery of Novel Integrase Inhibitors Acting outside the Active Site Through High-Throughput Screening. Molecules. 2019 24, . PubMed PMID:31614773

Lee GE, Mauro E, Parissi V, Shin CG, Lesbats P. Structural Insights on Retroviral DNA Integration: Learning from Foamy Viruses. Viruses. 2019 11, . PubMed PMID:31443391

Szöőr B, Simon DV, Rojas F, Young J, Robinson DR, Krüger T, Engstler M, Matthews KR. Positional Dynamics and Glycosomal Recruitment of Developmental Regulators during Trypanosome Differentiation. mBio. 2019 10, . PubMed PMID:31289175

Su X, Rak M, Tetaud E, Godard F, Sardin E, Bouhier M, Gombeau K, Caetano-Anollés D, Salin B, Chen H, di Rago JP, Tribouillard-Tanvier D. Deregulating mitochondrial metabolite and ion transport has beneficial effects in yeast and human cellular models for NARP syndrome. Hum Mol Genet. 2019 28, 3792-3804. PubMed PMID:31276579

Dauchy FA, Contin-Bordes C, Nzoumbou-Boko R, Bonhivers M, Landrein N, Robinson DR, Rambert J, Courtois P, Daulouède S, Vincendeau P. Trypanosoma brucei gambiense excreted/secreted factors impair lipopolysaccharide-induced maturation and activation of human monocyte-derived dendritic cells. Parasite Immunol. 2019 41, e12632. PubMed PMID:31099071

Corvaglia V, Carbajo D, Prabhakaran P, Ziach K, Mandal PK, Santos VD, Legeay C, Vogel R, Parissi V, Pourquier P, Huc I. Carboxylate-functionalized foldamer inhibitors of HIV-1 integrase and Topoisomerase 1: artificial analogues of DNA mimic proteins. Nucleic Acids Res. 2019 47, 5511-5521. PubMed PMID:31073604

Alves BM, Siqueira JD, Prellwitz IM, Botelho OM, Da Hora VP, Sanabani S, Recordon-Pinson P, Fleury H, Soares EA, Soares MA. Estimating HIV-1 Genetic Diversity in Brazil Through Next-Generation Sequencing. Front Microbiol. 2019 10, 749. PubMed PMID:31024510

Nkongolo S, Nußbaum L, Lempp FA, Wodrich H, Urban S, Ni Y. The retinoic acid receptor (RAR) α-specific agonist Am80 (tamibarotene) and other RAR agonists potently inhibit hepatitis B virus transcription from cccDNA. Antiviral Res. 2019 168, 146-155. PubMed PMID:31018112

Basmaciyan L, Robinson DR, Azas N, Casanova M. (De)glutamylation and cell death in Leishmania parasites. PLoS Negl Trop Dis. 2019 13, e0007264. PubMed PMID:31017892

Courtois P, Nabos P, Nzoumbou-Boko R, Reix CE, Dauchy FA, Daulouede S, Bringaud F, Robinson DR, Vincendeau P. Purification of Extracellular Trypanosomes, Including African, from Blood by Anion-Exchangers (Diethylaminoethyl-cellulose Columns). J Vis Exp. 2019 , . PubMed PMID:31009012

Richetta C, Thierry S, Thierry E, Lesbats P, Lapaillerie D, Munir S, Subra F, Leh H, Deprez E, Parissi V, Delelis O. Two-long terminal repeat (LTR) DNA circles are a substrate for HIV-1 integrase. J Biol Chem. 2019 294, 8286-8295. PubMed PMID:30971426

Laurian R, Dementhon K, Doumèche B, Soulard A, Noel T, Lemaire M, Cotton P. Hexokinase and Glucokinases Are Essential for Fitness and Virulence in the Pathogenic Yeast Candida albicans. Front Microbiol. 2019 10, 327. PubMed PMID:30858840

Tumiotto C, Alves BM, Recordon-Pinson P, Jourdain M, Bellecave P, Guidicelli GL, Visentin J, Bonnet F, Hessamfar M, Neau D, Sanchez J, Brander C, Sajadi M, Eyzaguirre L, Soares EA, Routy JP, Soares MA, Fleury H. Provir/Latitude 45 study: A step towards a multi-epitopic CTL vaccine designed on archived HIV-1 DNA and according to dominant HLA I alleles. PLoS One. 2019 14, e0212347. PubMed PMID:30811489

Mauro E, Lesbats P, Lapaillerie D, Chaignepain S, Maillot B, Oladosu O, Robert X, Fiorini F, Kieffer B, Bouaziz S, Gouet P, Ruff M, Parissi V. Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase. Nucleic Acids Res. 2019 47, 3607-3618. PubMed PMID:30767014

Coutton C, Martinez G, Kherraf ZE, Amiri-Yekta A, Boguenet M, Saut A, He X, Zhang F, Cristou-Kent M, Escoffier J, Bidart M, Satre V, Conne B, Fourati Ben Mustapha S, Halouani L, Marrakchi O, Makni M, Latrous H, Kharouf M, Pernet-Gallay K, Bonhivers M, Hennebicq S, Rives N, Dulioust E, Touré A, Gourabi H, Cao Y, Zouari R, Hosseini SH, Nef S, Thierry-Mieg N, Arnoult C, Ray PF. Bi-allelic Mutations in ARMC2 Lead to Severe Astheno-Teratozoospermia Due to Sperm Flagellum Malformations in Humans and Mice. Am J Hum Genet. 2019 104, 331-340. PubMed PMID:30686508

Florini F, Naguleswaran A, Gharib WH, Bringaud F, Roditi I. Unexpected diversity in eukaryotic transcription revealed by the retrotransposon hotspot family of Trypanosoma brucei. Nucleic Acids Res. 2019 47, 1725-1739. PubMed PMID:30544263

Accoceberry I, Couzigou C, Fitton-Ouhabi V, Biteau N, Noël T. Challenging SNP impact on caspofungin resistance by full-length FKS1 allele replacement in Candida lusitaniae. J Antimicrob Chemother. 2019 74, 618-624. PubMed PMID:30517635

Fernandes PM, Kinkead J, McNae IW, Bringaud F, Michels PAM, Walkinshaw MD. The kinetic characteristics of human and trypanosomatid phosphofructokinases for the reverse reaction. Biochem J. 2019 476, 179-191. PubMed PMID:30404924

2018

Wargnies M, Bertiaux E, Cahoreau E, Ziebart N, Crouzols A, Morand P, Biran M, Allmann S, Hubert J, Villafraz O, Millerioux Y, Plazolles N, Asencio C, Rivière L, Rotureau B, Boshart M, Portais JC, Bringaud F. Gluconeogenesis is essential for trypanosome development in the tsetse fly vector. PLoS Pathog. 2018 14, e1007502. PubMed PMID:30557412

Lesbats P, Parissi V. Retroviral integration site selection: a running Gag?. Microb Cell. 2018 5, 569-571. PubMed PMID:30533422

Pineda E, Thonnus M, Mazet M, Mourier A, Cahoreau E, Kulyk H, Dupuy JW, Biran M, Masante C, Allmann S, Rivière L, Rotureau B, Portais JC, Bringaud F. Glycerol supports growth of the Trypanosoma brucei bloodstream forms in the absence of glucose: Analysis of metabolic adaptations on glycerol-rich conditions. PLoS Pathog. 2018 14, e1007412. PubMed PMID:30383867

Cirri E, Brier S, Assal R, Canul-Tec JC, Chamot-Rooke J, Reyes N. Consensus designs and thermal stability determinants of a human glutamate transporter. Elife. 2018 7, . PubMed PMID:30334738

Martinez G, Kherraf ZE, Zouari R, Fourati Ben Mustapha S, Saut A, Pernet-Gallay K, Bertrand A, Bidart M, Hograindleur JP, Amiri-Yekta A, Kharouf M, Karaouzène T, Thierry-Mieg N, Dacheux-Deschamps D, Satre V, Bonhivers M, Touré A, Arnoult C, Ray PF, Coutton C. Whole-exome sequencing identifies mutations in FSIP2 as a recurrent cause of multiple morphological abnormalities of the sperm flagella. Hum Reprod. 2018 33, 1973-1984. PubMed PMID:30137358

Kherraf ZE, Amiri-Yekta A, Dacheux D, Karaouzène T, Coutton C, Christou-Kent M, Martinez G, Landrein N, Le Tanno P, Fourati Ben Mustapha S, Halouani L, Marrakchi O, Makni M, Latrous H, Kharouf M, Pernet-Gallay K, Gourabi H, Robinson DR, Crouzy S, Blum M, Thierry-Mieg N, Touré A, Zouari R, Arnoult C, Bonhivers M, Ray PF. A Homozygous Ancestral SVA-Insertion-Mediated Deletion in WDR66 Induces Multiple Morphological Abnormalities of the Sperm Flagellum and Male Infertility. Am J Hum Genet. 2018 103, 400-412. PubMed PMID:30122540

Zhao XZ, Métifiot M, Kiselev E, Kessl JJ, Maddali K, Marchand C, Kvaratskhelia M, Pommier Y, Burke TR Jr. HIV-1 Integrase-Targeted Short Peptides Derived from a Viral Protein R Sequence. Molecules. 2018 23, . PubMed PMID:30049955

Robert-Gangneux F, Meroni V, Dupont D, Botterel F, Garcia JMA, Brenier-Pinchart MP, Accoceberry I, Akan H, Abbate I, Boggian K, Bruschi F, Carratalà J, David M, Drgona L, Djurković-Djaković O, Farinas MC, Genco F, Gkrania-Klotsas E, Groll AH, Guy E, Hirzel C, Khanna N, Kurt Ö, Junie LM, Lazzarotto T, Len O, Mueller NJ, Munoz P, Pana ZD, Roilides E, Stajner T, van Delden C, Villena I, Pelloux H, Manuel O. Toxoplasmosis in Transplant Recipients, Europe, 2010-2014. Emerg Infect Dis. 2018 24, 1497-1504. PubMed PMID:30014843

Komatsu T, Quentin-Froignant C, Carlon-Andres I, Lagadec F, Rayne F, Ragues J, Kehlenbach RH, Zhang W, Ehrhardt A, Bystricky K, Morin R, Lagarde JM, Gallardo F, Wodrich H. In Vivo Labelling of Adenovirus DNA Identifies Chromatin Anchoring and Biphasic Genome Replication. J Virol. 2018 92, . PubMed PMID:29997215

Recordon-Pinson P, Alves BM, Tumiotto C, Bellecave P, Bonnet F, Neau D, Soares EA, Soares MA, Fleury H. A New HIV-1 Circulating Recombinant Form (CRF98_cpx) Between CRF06_cpx and Subtype B Identified in Southwestern France. AIDS Res Hum Retroviruses. 2018 34, 1005-1009. PubMed PMID:29947242

Millerioux Y, Mazet M, Bouyssou G, Allmann S, Kiema TR, Bertiaux E, Fouillen L, Thapa C, Biran M, Plazolles N, Dittrich-Domergue F, Crouzols A, Wierenga RK, Rotureau B, Moreau P, Bringaud F. De novo biosynthesis of sterols and fatty acids in the Trypanosoma brucei procyclic form: Carbon source preferences and metabolic flux redistributions. PLoS Pathog. 2018 14, e1007116. PubMed PMID:29813135

Jaubert C, Bedrat A, Bartolucci L, Di Primo C, Ventura M, Mergny JL, Amrane S, Andreola ML. RNA synthesis is modulated by G-quadruplex formation in Hepatitis C virus negative RNA strand. Sci Rep. 2018 8, 8120. PubMed PMID:29802381

Marchese L, Nascimento JF, Damasceno FS, Bringaud F, Michels PAM, Silber AM. The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids. Pathogens. 2018 7, . PubMed PMID:29614775

Ziach K, Chollet C, Parissi V, Prabhakaran P, Marchivie M, Corvaglia V, Bose PP, Laxmi-Reddy K, Godde F, Schmitter JM, Chaignepain S, Pourquier P, Huc I. Single helically folded aromatic oligoamides that mimic the charge surface of double-stranded B-DNA. Nat Chem. 2018 10, 511-518. PubMed PMID:29610464

Dong FN, Amiri-Yekta A, Martinez G, Saut A, Tek J, Stouvenel L, Lorès P, Karaouzène T, Thierry-Mieg N, Satre V, Brouillet S, Daneshipour A, Hosseini SH, Bonhivers M, Gourabi H, Dulioust E, Arnoult C, Touré A, Ray PF, Zhao H, Coutton C. Absence of CFAP69 Causes Male Infertility due to Multiple Morphological Abnormalities of the Flagella in Human and Mouse. Am J Hum Genet. 2018 102, 636-648. PubMed PMID:29606301

Kovářová J, Pountain AW, Wildridge D, Weidt S, Bringaud F, Burchmore RJS, Achcar F, Barrett MP. Deletion of transketolase triggers a stringent metabolic response in promastigotes and loss of virulence in amastigotes of Leishmania mexicana. PLoS Pathog. 2018 14, e1006953. PubMed PMID:29554142

Coutton C, Vargas AS, Amiri-Yekta A, Kherraf ZE, Ben Mustapha SF, Le Tanno P, Wambergue-Legrand C, Karaouzène T, Martinez G, Crouzy S, Daneshipour A, Hosseini SH, Mitchell V, Halouani L, Marrakchi O, Makni M, Latrous H, Kharouf M, Deleuze JF, Boland A, Hennebicq S, Satre V, Jouk PS, Thierry-Mieg N, Conne B, Dacheux D, Landrein N, Schmitt A, Stouvenel L, Lorès P, El Khouri E, Bottari SP, Fauré J, Wolf JP, Pernet-Gallay K, Escoffier J, Gourabi H, Robinson DR, Nef S, Dulioust E, Zouari R, Bonhivers M, Touré A, Arnoult C, Ray PF. Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human. Nat Commun. 2018 9, 686. PubMed PMID:29449551

Tumiotto C, Bellecave P, Recordon-Pinson P, Groppi A, Nikolski M, Fleury H. Diversity of HIV-1 in Aquitaine, Southwestern France, 2012-2016. AIDS Res Hum Retroviruses. 2018 34, 471-473. PubMed PMID:29439582

Lorès P, Coutton C, El Khouri E, Stouvenel L, Givelet M, Thomas L, Rode B, Schmitt A, Louis B, Sakheli Z, Chaudhry M, Fernandez-Gonzales A, Mitsialis A, Dacheux D, Wolf JP, Papon JF, Gacon G, Escudier E, Arnoult C, Bonhivers M, Savinov SN, Amselem S, Ray PF, Dulioust E, Touré A. Homozygous missense mutation L673P in adenylate kinase 7 (AK7) leads to primary male infertility and multiple morphological anomalies of the flagella but not to primary ciliary dyskinesia. Hum Mol Genet. 2018 27, 1196-1211. PubMed PMID:29365104

Accoceberry I, Rougeron A, Biteau N, Chevrel P, Fitton-Ouhabi V, Noël T. A CTG Clade Candida Yeast Genetically Engineered for the Genotype-Phenotype Characterization of Azole Antifungal Resistance in Human-Pathogenic Yeasts. Antimicrob Agents Chemother. 2018 62, . PubMed PMID:29038279

2017

Benleulmi MS, Matysiak J, Robert X, Miskey C, Mauro E, Lapaillerie D, Lesbats P, Chaignepain S, Henriquez DR, Calmels C, Oladosu O, Thierry E, Leon O, Lavigne M, Andreola ML, Delelis O, Ivics Z, Ruff M, Gouet P, Parissi V. Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails. Retrovirology. 2017 14, 54. PubMed PMID:29179726

Albisetti A, Florimond C, Landrein N, Vidilaseris K, Eggenspieler M, Lesigang J, Dong G, Robinson DR, Bonhivers M. Interaction between the flagellar pocket collar and the hook complex via a novel microtubule-binding protein in Trypanosoma brucei. PLoS Pathog. 2017 13, e1006710. PubMed PMID:29091964

Garcia-Silva MR, Sollelis L, MacPherson CR, Stanojcic S, Kuk N, Crobu L, Bringaud F, Bastien P, Pagès M, Scherf A, Sterkers Y. Identification of the centromeres of Leishmania major: revealing the hidden pieces. EMBO Rep. 2017 18, 1968-1977. PubMed PMID:28935715

Tumiotto C, Riviere L, Bellecave P, Recordon-Pinson P, Vilain-Parce A, Guidicelli GL, Fleury H, Provir/Latitude 45 collaborating group. Sanger and Next-Generation Sequencing data for characterization of CTL epitopes in archived HIV-1 proviral DNA. PLoS One. 2017 12, e0185211. PubMed PMID:28934310

Rayne F, Wittkop L, Bader C, Kassab S, Tumiotto C, Berciaud S, Wodrich H, Lafon ME, Typadeno Study Members. Rapid Adenovirus typing method for species identification. J Virol Methods. 2017 249, 156-160. PubMed PMID:28918074

Quilès F, Accoceberry I, Couzigou C, Francius G, Noël T, El-Kirat-Chatel S. AFM combined to ATR-FTIR reveals Candida cell wall changes under caspofungin treatment. Nanoscale. 2017 9, 13731-13738. PubMed PMID:28884772

Dannaoui E, Gabriel F, Gaboyard M, Lagardere G, Audebert L, Quesne G, Godichaud S, Verweij PE, Accoceberry I, Bougnoux ME. Molecular Diagnosis of Invasive Aspergillosis and Detection of Azole Resistance by a Newly Commercialized PCR Kit. J Clin Microbiol. 2017 55, 3210-3218. PubMed PMID:28814586

Durrens P, Klopp C, Biteau N, Fitton-Ouhabi V, Dementhon K, Accoceberry I, Sherman DJ, Noël T. Genome Sequence of the Yeast Clavispora lusitaniae Type Strain CBS 6936. Genome Announc. 2017 5, . PubMed PMID:28774979

Matysiak J, Lesbats P, Mauro E, Lapaillerie D, Dupuy JW, Lopez AP, Benleulmi MS, Calmels C, Andreola ML, Ruff M, Llano M, Delelis O, Lavigne M, Parissi V. Modulation of chromatin structure by the FACT histone chaperone complex regulates HIV-1 integration. Retrovirology. 2017 14, 39. PubMed PMID:28754126

Zhao XZ, Smith SJ, Maskell DP, Métifiot M, Pye VE, Fesen K, Marchand C, Pommier Y, Cherepanov P, Hughes SH, Burke TR Jr. Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors. J Med Chem. 2017 60, 7315-7332. PubMed PMID:28737946

Sbicca L, González AL, Gresika A, Di Giorgio A, Closa JT, Tejedor RE, Andréola ML, Azoulay S, Patino N. Exploring the impact of the side-chain length on peptide/RNA binding events. Phys Chem Chem Phys. 2017 19, 18452-18460. PubMed PMID:28681892

Montespan C, Wiethoff CM, Wodrich H. A Small Viral PPxY Peptide Motif To Control Antiviral Autophagy. J Virol. 2017 91, . PubMed PMID:28659475

Normand AC, Becker P, Gabriel F, Cassagne C, Accoceberry I, Gari-Toussaint M, Hasseine L, De Geyter D, Pierard D, Surmont I, Djenad F, Donnadieu JL, Piarroux M, Ranque S, Hendrickx M, Piarroux R. Validation of a New Web Application for Identification of Fungi by Use of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry. J Clin Microbiol. 2017 55, 2661-2670. PubMed PMID:28637907

Smith TK, Bringaud F, Nolan DP, Figueiredo LM. Metabolic reprogramming during the Trypanosoma brucei life cycle. F1000Res. 2017 6, . PubMed PMID:28620452

Calmels C, Ventura M, Aknin C, Métifiot M, Andreola ML. De novo RNA synthesis catalyzed by the Zika Virus RNA polymerase domain. Sci Rep. 2017 7, 2697. PubMed PMID:28577343

Jaspart A, Calmels C, Cosnefroy O, Bellecave P, Pinson P, Claverol S, Guyonnet-Dupérat V, Dartigues B, Benleulmi MS, Mauro E, Gretteau PA, Parissi V, Métifiot M, Andreola ML. GCN2 phosphorylates HIV-1 integrase and decreases HIV-1 replication by limiting viral integration. Sci Rep. 2017 7, 2283. PubMed PMID:28536474

Navarro-Arias MJ, Dementhon K, Defosse TA, Foureau E, Courdavault V, Clastre M, Le Gal S, Nevez G, Le Govic Y, Bouchara JP, Giglioli-Guivarc'h N, Noël T, Mora-Montes HM, Papon N. Group X hybrid histidine kinase Chk1 is dispensable for stress adaptation, host-pathogen interactions and virulence in the opportunistic yeast Candida guilliermondii. Res Microbiol. 2017 168, 644-654. PubMed PMID:28499956

Canul-Tec JC, Assal R, Cirri E, Legrand P, Brier S, Chamot-Rooke J, Reyes N. Structure and allosteric inhibition of excitatory amino acid transporter 1. Nature. 2017 544, 446-451. PubMed PMID:28424515

Saltel F, Giese A, Azzi L, Elatmani H, Costet P, Ezzoukhry Z, Dugot-Senant N, Miquerol L, Boussadia O, Wodrich H, Dubus P, Jacquemin-Sablon H. Unr defines a novel class of nucleoplasmic reticulum involved in mRNA translation. J Cell Sci. 2017 130, 1796-1808. PubMed PMID:28386023

Thonnus M, Guérin A, Rivière L. A multigene family encoding surface glycoproteins in Trypanosoma congolense. Microb Cell. 2017 4, 90-97. PubMed PMID:28357394

2016

Navarro-Arias MJ, Defosse TA, Dementhon K, Csonka K, Mellado-Mojica E, Dias Valério A, González-Hernández RJ, Courdavault V, Clastre M, Hernández NV, Pérez-García LA, Singh DK, Vizler C, Gácser A, Almeida RS, Noël T, López MG, Papon N, Mora-Montes HM. Disruption of Protein Mannosylation Affects Candida guilliermondii Cell Wall, Immune Sensing, and Virulence. Front Microbiol. 2016 7, 1951. PubMed PMID:27994582

Biéler S, Waltenberger H, Barrett MP, McCulloch R, Mottram JC, Carrington M, Schwaeble W, McKerrow J, Phillips MA, Michels PA, Büscher P, Sanchez JC, Bishop R, Robinson DR, Bangs J, Ferguson M, Nerima B, Albertini A, Michel G, Radwandska M, Ndung'u JM. Evaluation of Antigens for Development of a Serological Test for Human African Trypanosomiasis. PLoS One. 2016 11, e0168074. PubMed PMID:27936225

Dauchy FA, Bonhivers M, Landrein N, Dacheux D, Courtois P, Lauruol F, Daulouède S, Vincendeau P, Robinson DR. Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model. PLoS Negl Trop Dis. 2016 10, e0005125. PubMed PMID:27855164

Quemener C, Baud J, Boyé K, Dubrac A, Billottet C, Soulet F, Darlot F, Dumartin L, Sire M, Grepin R, Daubon T, Rayne F, Wodrich H, Couvelard A, Pineau R, Schilling M, Castronovo V, Sue SC, Clarke K, Lomri A, Khatib AM, Hagedorn M, Prats H, Bikfalvi A. Dual Roles for CXCL4 Chemokines and CXCR3 in Angiogenesis and Invasion of Pancreatic Cancer. Cancer Res. 2016 76, 6507-6519. PubMed PMID:27634764

Komatsu T, Nagata K, Wodrich H. The Role of Nuclear Antiviral Factors against Invading DNA Viruses: The Immediate Fate of Incoming Viral Genomes. Viruses. 2016 8, . PubMed PMID:27782081

Komatsu T, Robinson DR, Hisaoka M, Ueshima S, Okuwaki M, Nagata K, Wodrich H. Tracking adenovirus genomes identifies morphologically distinct late DNA replication compartments. Traffic. 2016 17, 1168-1180. PubMed PMID:27492875

Austin S, Taouji S, Chevet E, Wodrich H, Rayne F. Using AlphaScreen(®) to Identify Small-Molecule Inhibitors Targeting a Conserved Host-Pathogen Interaction. Methods Mol Biol. 2016 1449, 453-67. PubMed PMID:27613056

Pasi M, Mornico D, Volant S, Juchet A, Batisse J, Bouchier C, Parissi V, Ruff M, Lavery R, Lavigne M. DNA minicircles clarify the specific role of DNA structure on retroviral integration. Nucleic Acids Res. 2016 44, 7830-47. PubMed PMID:27439712

Métifiot M, Johnson BC, Kiselev E, Marler L, Zhao XZ, Burke TR Jr, Marchand C, Hughes SH, Pommier Y. Selectivity for strand-transfer over 3'-processing and susceptibility to clinical resistance of HIV-1 integrase inhibitors are driven by key enzyme-DNA interactions in the active site. Nucleic Acids Res. 2016 44, 6896-906. PubMed PMID:27369381

Bougnoux ME, Dannaoui E, Accoceberry I, Angoulvant A, Bailly E, Botterel F, Chevrier S, Chouaki T, Cornet M, Dalle F, Datry A, Dupuis A, Fekkar A, Gangneux JP, Guitard J, Hennequin C, Le Govic Y, Le Pape P, Maubon D, Ranque S, Sautour M, Sendid B, Chandenier J. Multicenter Comparison of the Etest and EUCAST Methods for Antifungal Susceptibility Testing of Candida Isolates to Micafungin. Antimicrob Agents Chemother. 2016 60, 5088-91. PubMed PMID:27297480

Garrigue I, Moulinas R, Recordon-Pinson P, Delacour ML, Essig M, Kaminski H, Rerolle JP, Merville P, Fleury H, Alain S. Contribution of next generation sequencing to early detection of cytomegalovirus UL97 emerging mutants and viral subpopulations analysis in kidney transplant recipients. J Clin Virol. 2016 80, 74-81. PubMed PMID:27214758

Morales J, Hashimoto M, Williams TA, Hirawake-Mogi H, Makiuchi T, Tsubouchi A, Kaga N, Taka H, Fujimura T, Koike M, Mita T, Bringaud F, Concepción JL, Hashimoto T, Embley TM, Nara T. Differential remodelling of peroxisome function underpins the environmental and metabolic adaptability of diplonemids and kinetoplastids. Proc Biol Sci. 2016 283, . PubMed PMID:27170716

Billamboz M, Suchaud V, Bailly F, Lion C, Andréola ML, Christ F, Debyser Z, Cotelle P. 2-hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs) as human immunodeficiency virus type 1 integrase inhibitors: Influence of the alkylcarboxamide substitution of position 4. Eur J Med Chem. 2016 117, 256-68. PubMed PMID:27105029

Harijan RK, Mazet M, Kiema TR, Bouyssou G, Alexson SE, Bergmann U, Moreau P, Michels PA, Bringaud F, Wierenga RK. The SCP2-thiolase-like protein (SLP) of Trypanosoma brucei is an enzyme involved in lipid metabolism. Proteins. 2016 84, 1075-96. PubMed PMID:27093562

Komatsu T, Will H, Nagata K, Wodrich H. Imaging analysis of nuclear antiviral factors through direct detection of incoming adenovirus genome complexes. Biochem Biophys Res Commun. 2016 473, 200-205. PubMed PMID:27012198

Escudero JA, Loot C, Parissi V, Nivina A, Bouchier C, Mazel D. Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation. Nat Commun. 2016 7, 10937. PubMed PMID:26961432

Perdomo D, Bonhivers M, Robinson DR. The Trypanosome Flagellar Pocket Collar and Its Ring Forming Protein-TbBILBO1. Cells. 2016 5, . PubMed PMID:26950156

Zhao XZ, Smith SJ, Maskell DP, Metifiot M, Pye VE, Fesen K, Marchand C, Pommier Y, Cherepanov P, Hughes SH, Burke TR Jr. HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant Mutant Integrases. ACS Chem Biol. 2016 11, 1074-81. PubMed PMID:26808478

Štáfková J, Mach J, Biran M, Verner Z, Bringaud F, Tachezy J. Mitochondrial pyruvate carrier in Trypanosoma brucei. Mol Microbiol. 2016 100, 442-56. PubMed PMID:26748989

Jackson AP, Otto TD, Aslett M, Armstrong SD, Bringaud F, Schlacht A, Hartley C, Sanders M, Wastling JM, Dacks JB, Acosta-Serrano A, Field MC, Ginger ML, Berriman M. Kinetoplastid Phylogenomics Reveals the Evolutionary Innovations Associated with the Origins of Parasitism. Curr Biol. 2016 26, 161-172. PubMed PMID:26725202

2015

Komatsu T, Nagata K, Wodrich H. An Adenovirus DNA Replication Factor, but Not Incoming Genome Complexes, Targets PML Nuclear Bodies. J Virol. 2016 90, 1657-67. PubMed PMID:26608315

Sari O, Roy V, Métifiot M, Marchand C, Pommier Y, Bourg S, Bonnet P, Schinazi RF, Agrofoglio LA. Synthesis of dihydropyrimidine α,γ-diketobutanoic acid derivatives targeting HIV integrase. Eur J Med Chem. 2015 104, 127-38. PubMed PMID:26451771

Métifiot M, Amrane S, Mergny JL, Andreola ML. Anticancer molecule AS1411 exhibits low nanomolar antiviral activity against HIV-1. Biochimie. 2015 118, 173-5. PubMed PMID:26363100

Komatsu T, Dacheux D, Kreppel F, Nagata K, Wodrich H. A Method for Visualization of Incoming Adenovirus Chromatin Complexes in Fixed and Living Cells. PLoS One. 2015 10, e0137102. PubMed PMID:26332038

Austen JM, Reid SA, Robinson DR, Friend JA, Ditcham WG, Irwin PJ, Ryan U. Investigation of the morphological diversity of the potentially zoonotic Trypanosoma copemani in quokkas and Gilbert's potoroos. Parasitology. 2015 142, 1443-52. PubMed PMID:26160545

Naughtin M, Haftek-Terreau Z, Xavier J, Meyer S, Silvain M, Jaszczyszyn Y, Levy N, Miele V, Benleulmi MS, Ruff M, Parissi V, Vaillant C, Lavigne M. DNA Physical Properties and Nucleosome Positions Are Major Determinants of HIV-1 Integrase Selectivity. PLoS One. 2015 10, e0129427. PubMed PMID:26075397

Rodriguez C, Soulié C, Marcelin AG, Calvez V, Descamps D, Charpentier C, Flandre P, Recordon-Pinson P, Bellecave P, Pawlotsky JM, Masquelier B, ANRS AC11 Study Group. HIV-1 Coreceptor Usage Assessment by Ultra-Deep Pyrosequencing and Response to Maraviroc. PLoS One. 2015 10, e0127816. PubMed PMID:26068869

Thierry S, Benleulmi MS, Sinzelle L, Thierry E, Calmels C, Chaignepain S, Waffo-Teguo P, Merillon JM, Budke B, Pasquet JM, Litvak S, Ciuffi A, Sung P, Connell P, Hauber I, Hauber J, Andreola ML, Delelis O, Parissi V. Dual and Opposite Effects of hRAD51 Chemical Modulation on HIV-1 Integration. Chem Biol. 2015 22, 712-23. PubMed PMID:26051216

Pescatori L, Métifiot M, Chung S, Masoaka T, Cuzzucoli Crucitti G, Messore A, Pupo G, Madia VN, Saccoliti F, Scipione L, Tortorella S, Di Leva FS, Cosconati S, Marinelli L, Novellino E, Le Grice SF, Pommier Y, Marchand C, Costi R, Di Santo R. N-Substituted Quinolinonyl Diketo Acid Derivatives as HIV Integrase Strand Transfer Inhibitors and Their Activity against RNase H Function of Reverse Transcriptase. J Med Chem. 2015 58, 4610-23. PubMed PMID:25961960

Florimond C, Sahin A, Vidilaseris K, Dong G, Landrein N, Dacheux D, Albisetti A, Byard EH, Bonhivers M, Robinson DR. BILBO1 is a scaffold protein of the flagellar pocket collar in the pathogen Trypanosoma brucei. PLoS Pathog. 2015 11, e1004654. PubMed PMID:25822645

Thierry S, Munir S, Thierry E, Subra F, Leh H, Zamborlini A, Saenz D, Levy DN, Lesbats P, Saïb A, Parissi V, Poeschla E, Deprez E, Delelis O. Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration. Retrovirology. 2015 12, 24. PubMed PMID:25808736

Benleulmi MS, Matysiak J, Henriquez DR, Vaillant C, Lesbats P, Calmels C, Naughtin M, Leon O, Skalka AM, Ruff M, Lavigne M, Andreola ML, Parissi V. Intasome architecture and chromatin density modulate retroviral integration into nucleosome. Retrovirology. 2015 12, 13. PubMed PMID:25807893

Creek DJ, Mazet M, Achcar F, Anderson J, Kim DH, Kamour R, Morand P, Millerioux Y, Biran M, Kerkhoven EJ, Chokkathukalam A, Weidt SK, Burgess KE, Breitling R, Watson DG, Bringaud F, Barrett MP. Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose. PLoS Pathog. 2015 11, e1004689. PubMed PMID:25775470

Bringaud F, Biran M, Millerioux Y, Wargnies M, Allmann S, Mazet M. Combining reverse genetics and nuclear magnetic resonance-based metabolomics unravels trypanosome-specific metabolic pathways. Mol Microbiol. 2015 96, 917-26. PubMed PMID:25753950

Dacheux D, Roger B, Bosc C, Landrein N, Roche E, Chansel L, Trian T, Andrieux A, Papaxanthos-Roche A, Marthan R, Robinson DR, Bonhivers M. Human FAM154A (SAXO1) is a microtubule-stabilizing protein specific to cilia and related structures. J Cell Sci. 2015 128, 1294-307. PubMed PMID:25673876

Cuzzucoli Crucitti G, Métifiot M, Pescatori L, Messore A, Madia VN, Pupo G, Saccoliti F, Scipione L, Tortorella S, Esposito F, Corona A, Cadeddu M, Marchand C, Pommier Y, Tramontano E, Costi R, Di Santo R. Structure-activity relationship of pyrrolyl diketo acid derivatives as dual inhibitors of HIV-1 integrase and reverse transcriptase ribonuclease H domain. J Med Chem. 2015 58, 1915-28. PubMed PMID:25629256

Martinez R, Schellenberger P, Vasishtan D, Aknin C, Austin S, Dacheux D, Rayne F, Siebert A, Ruzsics Z, Gruenewald K, Wodrich H. The amphipathic helix of adenovirus capsid protein VI contributes to penton release and postentry sorting. J Virol. 2015 89, 2121-35. PubMed PMID:25473051

Cassany A, Ragues J, Guan T, Bégu D, Wodrich H, Kann M, Nemerow GR, Gerace L. Nuclear import of adenovirus DNA involves direct interaction of hexon with an N-terminal domain of the nucleoporin Nup214. J Virol. 2015 89, 1719-30. PubMed PMID:25410864

Bringaud F, Rogers M, Ghedin E. Identification and analysis of ingi-related retroposons in the trypanosomatid genomes. Methods Mol Biol. 2015 1201, 109-22. PubMed PMID:25388110

Shameer S, Logan-Klumpler FJ, Vinson F, Cottret L, Merlet B, Achcar F, Boshart M, Berriman M, Breitling R, Bringaud F, Bütikofer P, Cattanach AM, Bannerman-Chukualim B, Creek DJ, Crouch K, de Koning HP, Denise H, Ebikeme C, Fairlamb AH, Ferguson MA, Ginger ML, Hertz-Fowler C, Kerkhoven EJ, Mäser P, Michels PA, Nayak A, Nes DW, Nolan DP, Olsen C, Silva-Franco F, Smith TK, Taylor MC, Tielens AG, Urbaniak MD, van Hellemond JJ, Vincent IM, Wilkinson SR, Wyllie S, Opperdoes FR, Barrett MP, Jourdan F. TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei. Nucleic Acids Res. 2015 43, D637-44. PubMed PMID:25300491

2014

Allmann S, Mazet M, Ziebart N, Bouyssou G, Fouillen L, Dupuy JW, Bonneu M, Moreau P, Bringaud F, Boshart M. Triacylglycerol Storage in Lipid Droplets in Procyclic Trypanosoma brucei. PLoS One. 2014 9, e114628. PubMed PMID:25493940

Gabriel F, Accoceberry I, Bessoule JJ, Salin B, Lucas-Guérin M, Manon S, Dementhon K, Noël T. A Fox2-dependent fatty acid ß-oxidation pathway coexists both in peroxisomes and mitochondria of the ascomycete yeast Candida lusitaniae. PLoS One. 2014 9, e114531. PubMed PMID:25486052

Métifiot M, Amrane S, Litvak S, Andreola ML. G-quadruplexes in viruses: function and potential therapeutic applications. Nucleic Acids Res. 2014 42, 12352-66. PubMed PMID:25332402

Bosse JB, Virding S, Thiberge SY, Scherer J, Wodrich H, Ruzsics Z, Koszinowski UH, Enquist LW. Nuclear herpesvirus capsid motility is not dependent on F-actin. mBio. 2014 5, e01909-14. PubMed PMID:25293761

Korf K, Wodrich H, Haschke A, Ocampo C, Harder L, Gieseke F, Pollmann A, Dierck K, Prall S, Staege H, Ma H, Horstmann MA, Evans RM, Sternsdorf T. The PML domain of PML-RARα blocks senescence to promote leukemia. Proc Natl Acad Sci U S A. 2014 111, 12133-8. PubMed PMID:25092303

Papuchon J, Pinson P, Guidicelli GL, Bellecave P, Thomas R, LeBlanc R, Reigadas S, Taupin JL, Baril JG, Routy JP, Wainberg M, Fleury H, Provir/Latitude 45 study group. Kinetics of HIV-1 CTL epitopes recognized by HLA I alleles in HIV-infected individuals at times near primary infection: the Provir/Latitude45 study. PLoS One. 2014 9, e100452. PubMed PMID:24964202

Couzigou C, Gabriel F, Biteau N, Fitton-Ouhabi V, Noël T, Accoceberry I. Two missense mutations, E123Q and K151E, identified in the ERG11 allele of an azole-resistant isolate of Candida kefyr recovered from a stem cell transplant patient for acute myeloid leukemia. Med Mycol Case Rep. 2014 5, 12-5. PubMed PMID:24936404

Bellecave P, Malato L, Calmels C, Reigadas S, Parissi V, Andreola ML, Fleury H. In vitro analysis of the susceptibility of HIV-1 subtype A and CRF01_AE integrases to raltegravir. Int J Antimicrob Agents. 2014 44, 168-72. PubMed PMID:24935032

Zhao XZ, Smith SJ, Métifiot M, Marchand C, Boyer PL, Pommier Y, Hughes SH, Burke TR Jr. 4-amino-1-hydroxy-2-oxo-1,8-naphthyridine-containing compounds having high potency against raltegravir-resistant integrase mutants of HIV-1. J Med Chem. 2014 57, 5190-202. PubMed PMID:24901667

Gabriel F, Sabra A, El-Kirat-Chatel S, Pujol S, Fitton-Ouhabi V, Brèthes D, Dementhon K, Accoceberry I, Noël T. Deletion of the uracil permease gene confers cross-resistance to 5-fluorouracil and azoles in Candida lusitaniae and highlights antagonistic interaction between fluorinated nucleotides and fluconazole. Antimicrob Agents Chemother. 2014 58, 4476-85. PubMed PMID:24867971

Deramchia K, Morand P, Biran M, Millerioux Y, Mazet M, Wargnies M, Franconi JM, Bringaud F. Contribution of pyruvate phosphate dikinase in the maintenance of the glycosomal ATP/ADP balance in the Trypanosoma brucei procyclic form. J Biol Chem. 2014 289, 17365-78. PubMed PMID:24794874

Suchaud V, Bailly F, Lion C, Calmels C, Andréola ML, Christ F, Debyser Z, Cotelle P. Investigation of a novel series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as human immunodeficiency virus type 1 integrase inhibitors. J Med Chem. 2014 57, 4640-60. PubMed PMID:24793360

Simen BB, Braverman MS, Abbate I, Aerssens J, Bidet Y, Bouchez O, Gabriel C, Izopet J, Kessler HH, Stelzl E, Di Giallonardo F, Schlapbach R, Radonic A, Paredes R, Recordon-Pinson P, Sakwa J, St John EP, Schmitz-Agheguian GG, Metzner KJ, Däumer MP, 454 HIV Alphastudy Group. An international multicenter study on HIV-1 drug resistance testing by 454 ultra-deep pyrosequencing. J Virol Methods. 2014 204, 31-7. PubMed PMID:24731928

Costi R, Métifiot M, Chung S, Cuzzucoli Crucitti G, Maddali K, Pescatori L, Messore A, Madia VN, Pupo G, Scipione L, Tortorella S, Di Leva FS, Cosconati S, Marinelli L, Novellino E, Le Grice SF, Corona A, Pommier Y, Marchand C, Di Santo R. Basic quinolinonyl diketo acid derivatives as inhibitors of HIV integrase and their activity against RNase H function of reverse transcriptase. J Med Chem. 2014 57, 3223-34. PubMed PMID:24684270

Cougnoux A, Dalmasso G, Martinez R, Buc E, Delmas J, Gibold L, Sauvanet P, Darcha C, Déchelotte P, Bonnet M, Pezet D, Wodrich H, Darfeuille-Michaud A, Bonnet R. Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype. Gut. 2014 63, 1932-42. PubMed PMID:24658599

Amrane S, Kerkour A, Bedrat A, Vialet B, Andreola ML, Mergny JL. Topology of a DNA G-quadruplex structure formed in the HIV-1 promoter: a potential target for anti-HIV drug development. J Am Chem Soc. 2014 136, 5249-52. PubMed PMID:24649937

Porcel BM, Denoeud F, Opperdoes F, Noel B, Madoui MA, Hammarton TC, Field MC, Da Silva C, Couloux A, Poulain J, Katinka M, Jabbari K, Aury JM, Campbell DA, Cintron R, Dickens NJ, Docampo R, Sturm NR, Koumandou VL, Fabre S, Flegontov P, Lukeš J, Michaeli S, Mottram JC, Szöőr B, Zilberstein D, Bringaud F, Wincker P, Dollet M. The streamlined genome of Phytomonas spp. relative to human pathogenic kinetoplastids reveals a parasite tailored for plants. PLoS Genet. 2014 10, e1004007. PubMed PMID:24516393

Vandenhende MA, Bellecave P, Recordon-Pinson P, Reigadas S, Bidet Y, Bruyand M, Bonnet F, Lazaro E, Neau D, Fleury H, Dabis F, Morlat P, Masquelier B. Prevalence and evolution of low frequency HIV drug resistance mutations detected by ultra deep sequencing in patients experiencing first line antiretroviral therapy failure. PLoS One. 2014 9, e86771. PubMed PMID:24475178

Zhao XZ, Smith SJ, Métifiot M, Johnson BC, Marchand C, Pommier Y, Hughes SH, Burke TR Jr. Bicyclic 1-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide-containing HIV-1 integrase inhibitors having high antiviral potency against cells harboring raltegravir-resistant integrase mutants. J Med Chem. 2014 57, 1573-82. PubMed PMID:24471816

Schellenberger P, Kaufmann R, Siebert CA, Hagen C, Wodrich H, Grünewald K. High-precision correlative fluorescence and electron cryo microscopy using two independent alignment markers. Ultramicroscopy. 2014 143, 41-51. PubMed PMID:24262358

2013

Billamboz M, Suchaud V, Bailly F, Lion C, Demeulemeester J, Calmels C, Andréola ML, Christ F, Debyser Z, Cotelle P. 4-Substituted 2-Hydroxyisoquinoline-1,3(2H,4H)-diones as a Novel Class of HIV-1 Integrase Inhibitors. ACS Med Chem Lett. 2013 4, 606-11. PubMed PMID:24900718

Mazet M, Morand P, Biran M, Bouyssou G, Courtois P, Daulouède S, Millerioux Y, Franconi JM, Vincendeau P, Moreau P, Bringaud F. Revisiting the central metabolism of the bloodstream forms of Trypanosoma brucei: production of acetate in the mitochondrion is essential for parasite viability. PLoS Negl Trop Dis. 2013 7, e2587. PubMed PMID:24367711

Pflieger A, Waffo Teguo P, Papastamoulis Y, Chaignepain S, Subra F, Munir S, Delelis O, Lesbats P, Calmels C, Andreola ML, Merillon JM, Auge-Gouillou C, Parissi V. Natural stilbenoids isolated from grapevine exhibiting inhibitory effects against HIV-1 integrase and eukaryote MOS1 transposase in vitro activities. PLoS One. 2013 8, e81184. PubMed PMID:24312275

Porwal M, Cohen S, Snoussi K, Popa-Wagner R, Anderson F, Dugot-Senant N, Wodrich H, Dinsart C, Kleinschmidt JA, Panté N, Kann M. Parvoviruses cause nuclear envelope breakdown by activating key enzymes of mitosis. PLoS Pathog. 2013 9, e1003671. PubMed PMID:24204256

Škodová I, Verner Z, Bringaud F, Fabian P, Lukeš J, Horváth A. Characterization of two mitochondrial flavin adenine dinucleotide-dependent glycerol-3-phosphate dehydrogenases in Trypanosoma brucei. Eukaryot Cell. 2013 12, 1664-73. PubMed PMID:24142106

Costi R, Métifiot M, Esposito F, Cuzzucoli Crucitti G, Pescatori L, Messore A, Scipione L, Tortorella S, Zinzula L, Novellino E, Pommier Y, Tramontano E, Marchand C, Di Santo R. 6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach. J Med Chem. 2013 56, 8588-98. PubMed PMID:24124919

Martinez R, Burrage AM, Wiethoff CM, Wodrich H. High temporal resolution imaging reveals endosomal membrane penetration and escape of adenoviruses in real time. Methods Mol Biol. 2013 1064, 211-26. PubMed PMID:23996260

Bosse JB, Ragues J, Wodrich H. Fast generation of stable cell lines expressing fluorescent marker molecules to study pathogen induced processes. Methods Mol Biol. 2013 1064, 153-69. PubMed PMID:23996256

Millerioux Y, Ebikeme C, Biran M, Morand P, Bouyssou G, Vincent IM, Mazet M, Riviere L, Franconi JM, Burchmore RJ, Moreau P, Barrett MP, Bringaud F. The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control. Mol Microbiol. 2013 90, 114-29. PubMed PMID:23899193

Nomura W, Aikawa H, Ohashi N, Urano E, Métifiot M, Fujino M, Maddali K, Ozaki T, Nozue A, Narumi T, Hashimoto C, Tanaka T, Pommier Y, Yamamoto N, Komano JA, Murakami T, Tamamura H. Cell-permeable stapled peptides based on HIV-1 integrase inhibitors derived from HIV-1 gene products. ACS Chem Biol. 2013 8, 2235-44. PubMed PMID:23898787

Métifiot M, Marchand C, Pommier Y. HIV integrase inhibitors: 20-year landmark and challenges. Adv Pharmacol. 2013 67, 75-105. PubMed PMID:23885999

Papuchon J, Pinson P, Lazaro E, Reigadas S, Guidicelli G, Taupin JL, Neau D, Fleury H, Provir/Latitude 45 project. Resistance mutations and CTL epitopes in archived HIV-1 DNA of patients on antiviral treatment: toward a new concept of vaccine. PLoS One. 2013 8, e69029. PubMed PMID:23874854

Schreiner S, Wodrich H. Virion factors that target Daxx to overcome intrinsic immunity. J Virol. 2013 87, 10412-22. PubMed PMID:23864634

Capewell P, Monk S, Ivens A, Macgregor P, Fenn K, Walrad P, Bringaud F, Smith TK, Matthews KR. Regulation of Trypanosoma brucei Total and Polysomal mRNA during Development within Its Mammalian Host. PLoS One. 2013 8, e67069. PubMed PMID:23840587

Houard J, Aumelas A, Noël T, Pages S, Givaudan A, Fitton-Ouhabi V, Villain-Guillot P, Gualtieri M. Cabanillasin, a new antifungal metabolite, produced by entomopathogenic Xenorhabdus cabanillasii JM26. J Antibiot (Tokyo). 2013 66, 617-20. PubMed PMID:23756685

Allmann S, Morand P, Ebikeme C, Gales L, Biran M, Hubert J, Brennand A, Mazet M, Franconi JM, Michels PA, Portais JC, Boshart M, Bringaud F. Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux. J Biol Chem. 2013 288, 18494-505. PubMed PMID:23665470

Charbonneau V, Garrigue I, Jaquet A, Horo A, Minga A, Recordon-Pinson P, Dabis F, Fleury H. Dried cervical spots for human papillomaviruses identification. J Med Virol. 2013 85, 1222-8. PubMed PMID:23595602

Johnson BC, Métifiot M, Ferris A, Pommier Y, Hughes SH. A homology model of HIV-1 integrase and analysis of mutations designed to test the model. J Mol Biol. 2013 425, 2133-46. PubMed PMID:23542006

Cosnefroy O, Jaspart A, Calmels C, Parissi V, Fleury H, Ventura M, Reigadas S, Andréola ML. Activation of GCN2 upon HIV-1 infection and inhibition of translation. Cell Mol Life Sci. 2013 70, 2411-21. PubMed PMID:23417324

Recordon-Pinson P, Raymond S, Bellecave P, Marcelin AG, Soulie C, Descamps D, Calvez V, Harrigan PR, Fleury H, Izopet J, Masquelier B, S AC11 Resistance Study Group. HIV-1 dynamics and coreceptor usage in Maraviroc-treated patients with ongoing replication. Antimicrob Agents Chemother. 2013 57, 930-5. PubMed PMID:23208718